# Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure development (R61) followed by well-powered clinical trials (R33) to test the effectiveness of system interventions and strategies for improving the organization, delivery, coordination, and clinical and functional outcomes of mental health services. System interventions - which may span, for example, structural, policy, organizational, and interpersonal domains - attend to issues about the access, equity, engagement/utilization, value (cost/financing), management, or quality and safety of mental health services, with the goal of improved care processes and clinical and functional...

Canonical page: https://grantsonar.com/grants/opportunity/effectiveness-trials-to-test-mental-health-system-interventions-r61-r33--718e97f2-a8ad-4f45-9d36-ab76e7653c64
Source: grants_gov
Source ID: 357434
Last confirmed Oct 13, 2026 · Grants.gov
Deadline: October 15, 2027
Award size: not disclosed

## Answer-first Q&A

### Who is eligible for Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)?

Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required) eligibility includes eligible applicants named in the notice. Geographic eligibility is national or notice-specific geography; applicants should confirm the source notice before applying.

### What is the deadline for Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)?

Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required) has a listed deadline of October 15, 2027. Grant deadlines can change, so verify the current date with National Institutes of Health before submitting.

### How much funding is available for Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)?

Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required) lists an award size of not disclosed. Award ranges and total program funding are reported from the source metadata when available.

### Who funds Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)?

Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required) is funded by National Institutes of Health. GrantSonar tracks the notice with source ID 357434 from grants_gov.